| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e8d243dd9ab2a5005225c2bf2a84ed2d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-975 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6878
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2881
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-26 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2003-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2008-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bcc97e1769a3228546ea2a82019054d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb0fec0dd1a63b3b09ab927307e82886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31c743216f43f4f6897929a7a6803b95
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac33606c942e42f6696baa819c23cd17 |
| publicationDate |
2008-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7320894-B2 |
| titleOfInvention |
Diagnostic method for diseases by screening for hepcidin in human or animal tissues, blood or body fluids and therapeutic uses therefor |
| abstract |
The present invention concerns methods and kits for diagnosing a disease condition characterized by non-physiological levels of hepcidin, comprising obtaining a tissue or fluid sample from a subject; contacting the sample with an antibody or fragment thereof that specifically binds to a polypeptide corresponding to the mid-portion or C terminus of a hepcidin protein, and quantifying the hepcidin level using an assay based on binding of the antibody and the polypeptide; wherein the non-physiological level of hepcidin is indicative of the disease condition. The present invention also concerns diagnostic methods and kits for applications in genetic technological approaches, such as for overexpressing or downregulating hepcidin. The present invention further concerns therapeutic treatment of certain diseases by treatment of subjects with hepcidin and agonists or antagonists of hepcidin. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007224186-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8003338-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010330595-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010151487-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010086945-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7998691-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7820163-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8263352-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016049036-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8329174-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9803011-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006092351-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011027261-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10323088-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8304258-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010298159-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8304197-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8313950-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8017737-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011053268-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010068737-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10239941-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8187827-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9657098-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009136495-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8609817-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011189190-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8765129-B2 |
| priorityDate |
2002-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |