http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7301041-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b180e9f4d9a057dbdea36d6fdc73a60 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F17-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F17-00 |
| filingDate | 2003-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a82a4f8f3af82c1c81ff5b0f944b0dce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73405fdb3981d2f453184711be96230f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06c925377f5524d5c97b002a4ce48327 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56272c2249b5753365de39d9acd8b0f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1974dea041cebe2b4cbf6b901bd4cc25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_626f1ac868b8bb0945d986b9253f1ca6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_214b401d59d4e05f9b8683ae89a888f0 |
| publicationDate | 2007-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7301041-B2 |
| titleOfInvention | Bi-functional metallocenes, preparation process and use in the labeling or biological molecules |
| abstract | The invention relates to bi-functionalised metallocenes of general formula (I) where Me=a transition metal, preferably chosen from Fe, Ru and Os, Y and Z, when identical are selected from —(CH 2 ) n —O—, (CH 2 )—O—[(CH 2 ) 2 —O] P — and —(CH 2 ) q —CONH—(CH 2 ) r —O—, or Y=—(CH 2 ) S —NH— and Z=—(CH 2 ) t —COO—, n =a whole number from 3 to 6 inclusive, p=a whole number from 1 to 4 inclusive, q=a whole number from 0 to 2 inclusive, r=a whole number from 0 to 2 inclusive, s=a whole number from 2 to 5 inclusive, t=a whole number from 3 to 6 inclusive, R and R′=H atoms or are protective groups used in oligonucleotide and peptide synthesis, where at least one of R or R′ is protective group used in oligonucleotide and peptide synthesis and R and R′ are as defined below: (i) when Z and Y are selected from (CH 2 ) n —O—, —(CH 2 )—O—[(CH 2 ) 2 —O] p — and —(CH 2 ) q —CONH—(CH 2 ) r —O—, then R and R′ are protective groups used in oligonucleotide synthesis and R is a group which can leave a free OH group after deprotection, preferably a photolabile group such as monomethroxythoxytrityl, dimethoxytrityl, t-butyldimethylsilyl, acetyl or trifluroacetyl, and R′ is a phosphorylated group which can react with a free OH, preferably a phosphodiester, phosphoramidite or H-phosphonate and (ii) when Y=—(CH 2 ) s —NH— and Z=—(CH 2 ) t —COO—, then R is a protective group used in the synthesis of peptides and is an amino-protecting group, preferably 9-fluorenyloxycarbonyl, t-butoxycarbonyl or benzyloxycarbonyl and R′=H. The above is applied in marking. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9127308-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10094800-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9540405-B2 |
| priorityDate | 2002-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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