http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7282597-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6223bea7bd553fbad56cc0c78d55bc61 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65515 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-676 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-655 |
| filingDate | 2005-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_029a2cd6a28e76af104fcede27b75171 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8421e862bc4a35fcb5eaa441e5ce4466 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d22d4be8f6412e8b151142451ee3e4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc78c69fe0c5d7bc3d26195b4a65d89b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3279ea09aa2146cd4578eed27f2596d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0fb5c0e8ff2d53a9ba7b50f91fb43d1 |
| publicationDate | 2007-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7282597-B2 |
| titleOfInvention | Ascorbic acid derivatives and skin-whitening cosmetics |
| abstract | It is an object to provide an L-ascorbic acid derivative which can keep the L-ascorbic acid stable to heat and light and thus has a long shelf life, which is high in permeability into the skin, which can be quickly hydrolyzed by phosphatase, an enzyme that is ubiquitous in vivo, and which exhibits physiological activities that are inherent to L-ascorbic acid and beneficial to health, a method for producing such an L-ascorbic acid derivative, and a skin-whitening cosmetic material. n There is provided an ascorbic acid derivative comprising an L-ascorbic acid-2-phosphate ester or a salt thereof wherein the phosphate ester has a branched alkyl group, the L-ascorbic acid-2-phosphate ester being of formula [13]. The ascorbic acid derivative is produced by a method comprising reacting a branched alkanol with phosphorus oxychloride to synthesize monoalkyldichlorophosphate or dialkylmonochlorophosphate, reacting the thus obtained substance with 5,6-O-isopropylidene-L-ascorbic acid obtained by reacting L-ascorbic acid with acetone, and subjecting the thus obtained substance to acid hydrolysis. There is also provided a cosmetic material containing such an ascorbic acid derivative by 0.05 to 80 percent by weight. n n(wherein each of R 1 and R 2 is a hydrogen (H) atom or an alkyl group having branches and including 3 to 30 carbon atoms, but not both of R 1 and R 2 are hydrogen (H) atoms). |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7569211-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008253982-A1 |
| priorityDate | 2004-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 345.