Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f82940e47ba7a1188f8e2ffca55e0f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00581 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00722 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00599 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00596 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-06 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B30-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-0046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B70-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B20-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6845 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B70-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N24-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
filingDate |
2003-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2007-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_731b29a655bf84fdc49b046484400bf9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a760703f1d8e68535c348b671435669b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56e5c5036f41e672d4f6cf92b01a74b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9ca6de64eeb02c108fb37bc16edb704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45dff8cefd300fac3c98bf8ab4d220ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db4c93047eb77d69449bc11dd2857dbc |
publicationDate |
2007-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7269519-B2 |
titleOfInvention |
Method for producing and screening mass-coded combinatorial libraries for drug discovery and target validation |
abstract |
The present invention provides a method for identifying a member of a mass-coded combinatorial library which is a ligand for biomolecule and assessing the effect of the binding of the ligand to the biomolecule. The mass-coded molecular library comprises compounds of the general formula XY n , wherein n is an integer from 2 to about 6, X is a scaffold and each Y is, independently, a peripheral moiety. The mass-coded combinatorial library is produced by reacting a scaffold precursor with a sufficient number of distant peripheral moiety precursors such that there exist at least about 250 distinct combinations of n peripheral moieties derived from the peripheral moiety precursors. |
priorityDate |
1998-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |