http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7262032-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f668a29d4b1c3f7c015b5c73ab27d88f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f1aa38bf38911c31c75f2cd562e8285 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-64 |
| filingDate | 2005-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d4b1396634238a001d587e41c91197c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61c529c9526d6ecc0e1a8ae4a770ae33 |
| publicationDate | 2007-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7262032-B2 |
| titleOfInvention | Allele-specific mutation detection assay using an enzyme-disabling agent |
| abstract | The present invention relates to a method of detecting a base at a pre-determined position in a nucleic acid molecule by performing enzymatic detection reactions using base-specific detection oligomers, where each oligomer is specific for a particular base at the predetermined position, and then comparing the enzymatic detection reactions to determine which base is present at the position, with an enzyme-disabling agent being present during the enzymatic detection reaction. In preferred embodiments the enzymatic detection reaction is an oligomer elongation extension reaction, catalysed by, among others, polymerase or ligase. Also disclosed are methods of performing the assay in a liquid phase and on microarrays. |
| priorityDate | 2003-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 528.