Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcff13f8573db698307f919e6385d5c4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-802 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2017-22082 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2017-22084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2017-22038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-254 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2017-22054 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L29-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6957 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B17-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B17-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L29-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
filingDate |
2001-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2007-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fdc535541353a2508559cc06173350c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d9ca458d64d004f7c77a817ed11ad66 |
publicationDate |
2007-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7238673-B2 |
titleOfInvention |
Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor |
abstract |
A method for the direct in vivo transformation of cells in and surrounding a solid tumor is disclosed. This method is based on the site-specific delivery of proteins to solid tumors and to tissue surrounding the solid tumor by direct injection of a nucleic acid sequence. In particular, this method is directed to site-specific delivery of nucleic acids encoding major histocompatibility proteins, cytokines, and toxins to a solid tumor. This technique provides for the transfer of vectors and expression of recombinant genes in vivo and allows the introduction of proteins of therapeutic or diagnostic value for the treatment of disease. |
priorityDate |
1989-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |