| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a6a9431aa1fe5109ca95ad4e332231b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-543
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
| filingDate |
2000-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2007-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e98d3113fac662d494332825008752f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_532879291b9f21fce2f5e6a9cf805f25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eabb9565c330c65e5c671c90ad76fdea |
| publicationDate |
2007-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7235234-B1 |
| titleOfInvention |
Bacterial delivery system |
| abstract |
We describe a bacterial delivery system for the delivery of DNA and antigens into cells. We constructed an attenuated bacterial vector which enters mammalian cells and ruptures delivering functional plasmid DNA and antigens into the cell cytoplasm. This Shigella vector was designed to deliver DNA to colonic surfaces, thus opening the possibility of oral and other mucosal DNA immunization and gene therapy strategies. The attenuated Shigella is also useful as a vaccine for reducing disease symptoms caused by Shigella. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11129906-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007134214-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11180535-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11406702-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10973908-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10501746-B1 |
| priorityDate |
1995-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |