Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5ad8562c578b061df7a2c3aee9d0e24 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-02 |
filingDate |
2005-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2007-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b67f1e0b4d10145e6eda2c4ba552e1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b323a9356868b8abf730237a91beb136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_948e60c08f0d5e679f6c1c149ca8d47a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a3e6ed53cb5d514566ac23aecde5552 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f630ba8658f6df0aafcf5434af981cfb |
publicationDate |
2007-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7223874-B2 |
titleOfInvention |
Bicyclic tetrahydrofuran lactone derivatives and process for the preparation thereof |
abstract |
The present invention relates to bicyclic tetrahydrofuran lactone derivatives of Formula (1) and a preparation method thereof, and particularly it relates to a process of preparing compounds of Formula (1) by performing an intramolecular cyclization of tetrahydrofuran-allenic acid derivatives in the presence of a phenyl halide, a palladium catalyst and a base: n nwherein n is 1 or 2, and R is phenyl optionally substituted with C 1 –C 6 alkyl, C 1 –C 6 alkoxy, hydroxyl or C 1 –C 6 hydroxyalkyl group. |
priorityDate |
2005-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |