Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78941ed5a01bfbcd48376e1fdb485b19 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1003 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
filingDate |
2004-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2007-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a582c35eecd908b118a359ac4e783f40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ea14497ca26913b1412b9f4b63bcbed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8c4f76bf0d86981a5da4d1ca0c86cfc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faa889061818ee5fb40bd79375f2eb10 |
publicationDate |
2007-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7214510-B2 |
titleOfInvention |
Regulation of gene expression by protein methylation |
abstract |
The invention relates to the cDNA and deduced amino acid sequence of the Coactivator Associated arginine (R) Methyltransferase protein, CARM1. A method is described for the use CARM1 to regulate gene expression in vivo. CARM1 has also been used to methylate arginine residues of histones, synthetic peptides, and other proteins. A method to use CARM1 to screen for drugs that inhibit its methyltransferase activity is also described, as is a method to screen for drugs that modulate CARM1's interactions with other proteins. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008108093-A1 |
priorityDate |
1998-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |