Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-52 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52 |
filingDate |
2002-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2007-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94f18b34b02258bf878dd7d218ea89cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db2b9a8f5c63e244d8ef0d649fd3d4f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a94849a47844853da040a0efddeb1aa6 |
publicationDate |
2007-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7208472-B2 |
titleOfInvention |
Pharmaceutical compositions including variants of vascular endothelial cell growth factor having altered pharmacological properties |
abstract |
Described herein are pharmaceutical compositions including vascular endothelial cell growth factor (VEGF) variants having modifications in the C-terminal heparin binding domain. The variants exhibit reduced clearance rates for systemic administration generally at lower doses compared with native VEGF thus providing variants having longer availability for therapeutic effect. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006286636-A1 |
priorityDate |
1997-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |