| abstract |
Optically active 1-substituted phenyl-2-nitro alcohol derivatives having the formula (1) n nand the process for producing thereof, and 1-substituted phenyl-2-amino alcohol derivatives having the formula (2)n n nand the process for producing thereof from the optically active 1-substituted phenyl-2-nitro alcohol derivatives. From these nitro alcohols, pharmaceuticals such as (R)-albutamin and (R)-sarmeterol useful as a bronchodilator is obtained via optically active amino alcohols which are useful pharmaceutical intermediates. |