| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae2afa937c0bfa5a9836926c06bd4911 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-042
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1641 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 |
| filingDate |
2002-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2007-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_392e8154ceaeed64e20c6933e0a11a1d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75d427120a754af0681d85fb37a81d2b |
| publicationDate |
2007-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7204997-B2 |
| titleOfInvention |
Responsive microgel and methods related thereto |
| abstract |
A responsive microgel is provided which responds volumetrically and reversibly to a change in one or more aqueous conditions selected from the group consisting of (temperature, pH, and ionic conditions) comprised of an ionizable network of covalently cross-linked homopolymeric ionizable monomers wherein the ionizable network is covalently attached to an amphiphilic copolymer to form a plurality of ‘dangling chains’ and wherein the ‘dangling chains’ of amphiphilic copolymer form immobile micelle-like aggregates in aqueous solution. A responsive microgel is further provided that comprises at least one therapeutic entity and delivers a substantially linear and sustained release of the therapeutic entity under physiological conditions. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020247601-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8328023-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10526366-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010155323-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011033633-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10017461-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008193598-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018106615-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9534236-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9296847-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005196343-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8298596-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9650470-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9259689-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9758547-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10005814-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011201078-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9790484-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10035719-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8697031-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011217752-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007253899-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8846203-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8945896-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8329034-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8377672-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8435776-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8652582-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004258754-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8586338-B2 |
| priorityDate |
2002-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |