http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7202249-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 |
filingDate | 2003-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2007-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06b6e46abae9ba1c66cd67eadac50e92 |
publicationDate | 2007-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-7202249-B2 |
titleOfInvention | Antagonists of chemokine receptors |
abstract | Compounds are provided which are antagonists of chemokine receptor activity. n The compounds thereof have the structure n nincluding enantiomers, diastereomers, tautomers, pharmaceutically acceptable salts and solvates thereof wherein:n A, B, D, E, X and Y are selected from N or C, J and K are C, and at least one of A, B, D, E, X and Y is N; L is selected from O, NH and S, wherein L may be connected to any one of A, B, D, E, J, X, K or Y; M is CH or N; P is a bond or C═O, wherein P is connected to any one of J, X, K or Y; Z is C(═O)GR 2 or C(H) 2 GR 2 ; G is O or NH or none, or when Z is C(═O)GR 2 , G also includes 1, 2 propylene; n is 0–4; R 1 is selected from halogen, —CN, —CF 3 , substituted alkyl, aryl and heteroaryl; R 2 is a heterocyclyl containing at least one N; R 3 is selected from halogen, cyano, alkyl, substituted alkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl, wherein R 3 is connected to any one of A, B, D and E; R 4 and R 5 are H; or R 4 and R 5 may be taken together with the atoms to which they are attached to form a ring; and R 10 is selected from H, alkyl, substituted alkyl, alkenyl, substituted alkenyl; or E and R 10 may be taken together with the atoms to which they are attached to form a heteroaryl or heterocycloalkyl ring. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010113472-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009182142-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009182140-A1 |
priorityDate | 2002-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 981.