| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-743 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74 |
| filingDate |
2005-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2006-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71144c99e84ae321014b91d2bc04604a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c22793149b37f5ebb66b85d5bf3c8fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_382f00294fcc445a2183c694a68ef323
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16d7d272ff076aab5c175deebc65ea68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_982e273234dfcac0d8e5e4f18052a116 |
| publicationDate |
2006-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7138246-B2 |
| titleOfInvention |
Methods for identifying or screening for agents that modulate 17β-HSD3 |
| abstract |
Methods for determining whether a test agent inhibits a 17β-HSD3, the methods comprising: obtaining a recombinant host cell that expresses the 17β-HSD3; obtaining a reaction mixture comprising the 17β-HSD3, androstenedione, and the test agent; measuring the amount of testosterone in the reaction mixture by a scintillation proximity assay (SPA) using SPA beads conjugated with a testosterone-specific antibody, wherein when the amount of testosterone is lower in the presence of a test agent than in the absence of the test agent, the test agent is identified as an inhibitor of the 17β-HSD3. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010143187-A1 |
| priorityDate |
2004-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |