http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7130042-B2

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filingDate 2004-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2006-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db8680b3e14928c495a749b98ab00901
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publicationDate 2006-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-7130042-B2
titleOfInvention Dual axis fluorescence microscope with modulated input
abstract A dual beam confocal microscope is provided. An optical source assembly provides two mutually coherent optical beams differing in frequency by a frequency difference Δf. The two beams are received by focusing assemblies that provide two focused beams to a sample. The focused beams intersect at a beam intersection angle within a target region of the sample. The two focused beams have respective focal regions preferably overlapping with the target region. A detector receives radiation emitted from the sample, including radiation emitted from the target region. The detector output, responsive to received intensity, is filtered with an electrical filter to provide a filtered signal. The electrical filter has a frequency response H(f), where H(f) has a pass band including f=Δf and a stop band including f=0. Optionally, an optical filter and/or a collection assembly can be placed between the sample and detector.
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