| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78941ed5a01bfbcd48376e1fdb485b19 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-361
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C41-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C43-225 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-361
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-225
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-14 |
| filingDate |
2005-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2006-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fcee4f70e1c52f2d21e928f7eca9730
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e57fe76c9cb4758aad4b13066a25ce10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_766b0d91c0ab6a7b086baaf326c87d66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49c7d381a948c1c8ff0cc4f3097f214c |
| publicationDate |
2006-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7119232-B2 |
| titleOfInvention |
Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes |
| abstract |
(Benzenesulfonyl)difluoromethyl anion, in situ generated from difluoromethyl phenyl sulfone and a base, was found to easily undergo nucleophilic substitution reactions (S N 2) with primary alkyl halides, elemental halogens, and perfluoroalkyl halides with good selectivity. The formed (benzenesufonyl)difluoromethylalkanes are useful intermediates for the facile preparation of 1,1-difluoro-1-alkenes and difluoromethylalkanes. Thus, difluoromethyl phenyl sulfone acts as both “CF 2 ═” and “CF 2 H − ” synthons |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11028105-B2 |
| priorityDate |
2004-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |