| abstract |
A method for non-rigid registration and fusion of images with physiological modeled organ motions resulting from respiratory motion and cardiac motion that are mathematically modeled with physiological constraints. A method of combining images comprises the steps of obtaining a first image dataset ( 24 ) of a region of interest of a subject and obtaining a second image dataset ( 34 ) of the region of interest of the subject. Next, a general model of physiological motion for the region of interest is provided ( 142 ). The general model of physiological motion is adapted with data derived from the first image data set ( 140 ) to provide a subject specific physiological model ( 154 ). The subject specific physiological model is applied ( 172 ) to the second image dataset ( 150 ) to provide a combined image ( 122 ). |