Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9cb16f3933087407282046d3265c0c4e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-143333 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6862 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6858 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D57-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-447 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 |
filingDate |
2004-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2006-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5747bb84544ac32566eb62e2efbca32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c9c1785426fd5821f8e81b353190595 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7be2e1b02ae7accd62a89af0b8d3dbb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d15963621956fe03c8308d8fe7d920c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d624bd56e2cde73a1701252419aa984 |
publicationDate |
2006-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7115376-B2 |
titleOfInvention |
Method for distinguishing different-sequence polynucleotides |
abstract |
Method and composition for detecting one or more selected polynucleotide regions in a target polynucleotide. In one embodiment of the invention, a plurality of different-sequence probe pairs are added to a target polynucleotide, where each probe pair includes two polynucleotide probe elements which are complementary in sequence to adjacent portions of a selected one of the target sequences in the target polynucleotide. In each probe pair, one of the probe elements contains a non-polynucleotide polymer chain which imparts a distinctive mobility to the associated probe pair, when the elements in the pair are ligated. The other element in the pair contains a detectable reporter label. After the probe pairs have been allowed to hybridize with the target polynucleotide, the hybridized polynucleotides are treated under conditions effective to ligate the end subunits of target-bound probe elements when their end subunits are base-paired with adjacent target bases. The ligated probe pairs are then released from the target polynucleotide and separated electrophoretically in a sieving matrix, or chromatographically. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3418395-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014039092-A1 |
priorityDate |
1992-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |