| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-975 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate |
2000-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2006-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4e0ce8eb7389b461ff6adefdd5cc927
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d795dd09af569d15e25c1a76a2ff594 |
| publicationDate |
2006-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7115262-B1 |
| titleOfInvention |
Chimeric protein for prevention and treatment of HIV infection |
| abstract |
This invention relates to bispecific fusion proteins effective in viral neutralization. More specifically, such proteins have two different binding domains, an inducing-binding domain and an induced-binding domain, functionally linked by a peptide linker. Such proteins, nucleic acid molecules encoding them, and their production and use in preventing or treating viral infections are provided. One prototypical bispecific fusion protein is sCD4-SCFv(17b), in which a soluble CD4 fragment (containing domains D1 and D2) is fused to a single chain Fv portion of antibody 17b via a linker. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015077789-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017213695-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011046946-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10188727-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011046946-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9181224-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10246505-B2 |
| priorityDate |
1999-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |