abstract |
A compound of formula (I) or a salt, ester or amide thereof; where X is O, or S, S(O) or S(O) 2 or NR 10 where R 10 is hydrogen or C 1-6 alkyl, and R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 and R 9 are various specified organic groups. These compounds are inhibitors of aurora 2 kinase, and are useful in the treatment of cancer. |