| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87d22c1ed7acfa7baf9a4d5e0472843a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-815
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 |
| filingDate |
2001-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2006-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_285c1bcbfd0c63e0c1fd8f49383d118f |
| publicationDate |
2006-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7091032-B2 |
| titleOfInvention |
Expression of a human insulin precursor in P. pastoris |
| abstract |
Methylotrophic recombinant yeast strain producing human insulin precursor, the strain comprising, in its genome, a copy of a first DNA construction and a second DNA construction, wherein the constructions are capably of directing the expression and secretion of human insulin precursor of the formula B(1-30)-Y1-Y2-A(1-21), wherein Y1 is lysine or arginine; Y2 is lysine or arginine; B(1-30) is the B peptide of the human insulin; and B(1-21) is the A peptide of human insulin, and wherein the strain is yeast Pichia Pastoris . DNA constructions and method for obtaining the strain are also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8778659-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2930182-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8410048-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009067636-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7608583-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006167221-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103003438-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012309935-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009192073-A1 |
| priorityDate |
2000-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |