http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7087433-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate | 2002-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_041a7e1b5d1b3beca9c76e6698dc375b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5edad74b95ff4ace2a6a81620811450d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3b5559d665b2d54b29c05e5d83d4235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77fae8e8dd95bc639cfae6a6ee484c4e |
| publicationDate | 2006-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7087433-B2 |
| titleOfInvention | 7SK RNA regulated transcription |
| abstract | A method for altering transcription in a cell comprising an amount of active CDK9/cyclin, comprises the steps of: (a) introducing in the cell an agent which modulates the amount of active CDK9/cyclin in the cell, and thereby alters transcription in the cell, wherein the agent comprises an RNA selected from the group consisting of an RNA aptamer that specifically binds CDK9/cyclin, a CDK9/cyclin-binding domain of 7SK RNA, a 7SK RNA-binding antisense 7SK RNA domain, and a 7SK RNA-specific RNAi, and (b) detecting a resultant altering of transcription in the cell. n Methods for screening for an agent which modulates 7SK RNA-CDK9/cyclin binding generally comprise the steps of (a) incubating a mixture of 7SK RNA, CDK9/cyclin and a candidate agent under conditions wherein but for the presence of the agent, the 7SK RNA and CDK9/cyclin engage in a reference binding; and (b) detecting an agent-biased binding of the 7SK RNA to the CDK9/cyclin. |
| priorityDate | 2002-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.