| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_77d9bf55e6700374867763cc2c6acaff |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5255 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-19 |
| filingDate |
2002-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2006-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe495ffed995a3157012eee645482f50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c964ae15e9fde95ce16012f969efe34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ed90f8b3162d88fb0fb5f34c31fe628
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19f5d1e67f2e0127c94cd9f71421687d |
| publicationDate |
2006-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7087225-B2 |
| titleOfInvention |
Methods and compositions for treating metabolic bone diseases relating to human endokine alpha |
| abstract |
The present invention concerns methods for diagnosis and treatment of metabolic bone diseases and disorders using a novel member of the tumor necrosis factor (TNF) family of cytokines. In particular the invention provides methods of using the Endokine alpha protein and/or homomultimeric and/or heteromultimeric polypeptide complexes containing Endokine alpha, in the diagnosis, prognosis and treatment of metabolic bone diseases and disorders. Also provided by the invention are methods of using the Endokine alpha protein and/or homomultimeric and/or heteromultimeric polypeptide complexes containing Endokine alpha, in the diagnosis, prognosis and treatment of diseases and/or disorders associated with aberrant osteoclast development and/or activity. The present invention also provides isolated polynucleotides encoding polypeptides of the invention, antibodies thereto, and agonists and antagonists thereof, for use in the diagnosis, prognosis and treatment of metabolic bone diseases and disorders. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8728475-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9216181-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10232017-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9730947-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9011859-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9775899-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9724390-B2 |
| priorityDate |
2001-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |