http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7084173-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6463fb486151af5a7c3b460021d3c3cf |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-753 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-74 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-753 |
| filingDate | 2002-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09e686c3ba8bfebb85c114a0b0e8ae6f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79d195e3b8628b6d2fd7c8a63a65e991 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b733ea9fe9c76278e9e802a58d7181e |
| publicationDate | 2006-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7084173-B2 |
| titleOfInvention | Compounds that stimulate glucose utilization and methods of use |
| abstract | The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia n nwhereinn W is C 1 –C 6 alkyl, halogen, or aryl; Cyc is C 3 or C 4 cycloalkyl; p is 0–3 for Cyc being C 4 cycloalkyl and p=0–2 for Cyc being C 3 cycloalkyl; Y is O, S, or NR, where R═H, alkyl or aryl; X is O, S, NR, or CR 3 R 4 ; Z is H, alkyl, cycloalkyl, aryl or (cyclo)alkylcarbonyl; R 1 is H, alkyl, aryl or O; R 2 is H, alkyl or aryl; R 3 and R 4 are, independently, H, alkyl or aryl; and n is an integer from 1 to 10; or a pharmaceutically acceptable salt, ester or prodrug thereof. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009258835-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8202901-B2 |
| priorityDate | 2001-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 315.