http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7081360-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5311311811316271c856fde1b2209569 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 |
| filingDate | 1999-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1e5172ffb0e86f811f60be2bc6fba3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3c08f1245f616dc9f1a8b3965577e9f |
| publicationDate | 2006-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7081360-B2 |
| titleOfInvention | Expression of G protein-coupled receptors with altered ligand binding and/or coupling properties |
| abstract | Modified forms of G protein-coupled receptors which display altered ligand binding and/or coupling properties are provided as well as cells expressing such receptors and assays utilizing these cells for screening and identifying pharmaceutically effective compounds that specifically modulate the activity of a these modified forms of G protein coupled receptors. Yeast or mammalian cells can be used to express such receptors. The subject assays enable rapid screening of large numbers of compounds (e.g., compounds in a library) to identify those which are receptor agonists or antagonists. Compositions of matter, such as these novel receptors, novel recombinant yeast cells and novel gene constructs, are also provided. The instant assays provide a convenient format for discovering compounds which can be useful in modulating cellular function, as well as in understanding the pharmacology of compounds that specifically interact with these modified forms G protein coupled receptors. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10209239-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7504230-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010209931-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11092599-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11009502-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004161797-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010209413-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11460469-B2 |
| priorityDate | 1998-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 563.