Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af7e913ef0b005c0868e86c5e3ef95e1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0817 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-86 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
filingDate |
2003-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2006-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a818fcc9c0b148b3d1e6f446ed72ba0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d98e09844b94ab1bc7e9fefa55cfac5 |
publicationDate |
2006-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7074765-B2 |
titleOfInvention |
Synthetic peptide analogs of Arg-Pro-Pro-Gly-Phe as selective inhibitors of thrombin and thrombin activation of protease activated receptors 1 and 4 |
abstract |
The invention relates to compounds and methods for inhibiting human platelet aggregation, thrombosis and cell activation mediated by PAR1 and PAR4 using peptide analogs of Arg-Pro-Pro-Gly-Phe that contain one or more amino acid substitutions. The invention also includes screening methods for identifying compounds that inhibit thrombin mediated activities. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006276402-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7879792-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006140923-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015045283-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10299714-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8168230-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE46830-E http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9605046-B2 |
priorityDate |
2003-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |