| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1cded1dd9dcc9dac6c1d9e44d8c1f78f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-18 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6824
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-46 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate |
2001-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2006-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69d3a994a1718992d38b3ccbfe240bf3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fead02b851f40a942a8ae10ebbdc2df
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95e47a13b1e56f79eb3891d600c5c34b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b31353ef31819592d83fcc63fff062b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5eab5f18092d336d786c7c715a089c80 |
| publicationDate |
2006-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7074570-B2 |
| titleOfInvention |
Peptide fragmentation |
| abstract |
The present invention relates to a method of identifying a polypeptide using a class of novel, water-stable reagents. More specifically, the method according to the invention comprises the steps ofn (a) derivatization in an aqueous solution of the N-terminus of the polypeptide, or the N-termini of one or more peptides of the polypeptide, with at least one acidic reagent which comprises a sulfonyl moiety coupled to an activated acid moiety to provide one or more peptide derivatives; (b) analyzing at least one such derivative using a mass spectrometric technique to provide a fragmentation pattern; and (c) interpreting the fragmentation pattern. nn Furthermore, the present invention also relates to a kit for identifying a polypeptide by a mass spectrometric technique, which kit comprises at least one acidic reagent comprising a sulfonyl moiety coupled to an activated acid moiety in a container together with suitable means for analysis of the fragmentation pattern obtained. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11150248-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11371996-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11061023-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11035832-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11448652-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11747310-B2 |
| priorityDate |
2001-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |