Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_938a6d7a15cbc93a74abe1953eb25d47 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06N7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F17-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06G7-48 |
filingDate |
1999-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2006-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a58cf14c536737cd67b88f5db4020de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cae78a9aca49fa7b30874a6efdfea68e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_753e7e5d2929d7e62ea6cdd1f4a7dcad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63346ad01a844847b45cbd8b480681d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3bfceb96ba8ec0ef039a7ec9522e7fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a859122e948a7a75cf6b7f727ec814d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed48f10053a8145d3af9f8ca9887bda5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0248feeb0217051beb704c1df2c855b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77ab0e0ab3fe1adc4063dfbec265cb3d |
publicationDate |
2006-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7065452-B1 |
titleOfInvention |
Molecules comprising a calcineurin-like binding pocket and encoded data storage medium capable of graphically displaying them |
abstract |
The present invention relates to crystallized molecules and molecular complexes which comprise the active site binding pocket or the FKBP12/FK506 binding pocket of calcineurin or close structural homologues to either binding pocket. This invention also relates to a data storage material encoded with the corresponding structure coordinates of those crystallized molecules or molecular complexes. Such data storage material is capable of displaying such molecules and molecular complexes as a graphical three-dimensional representation on a computer screen. In addition, this invention relates to methods of using the structure coordinates of those molecules or molecular complexes to solve the structure of homologous proteins. This invention also relates to methods of using the structure coordinates to screen and design compounds that bind to calcineurin or homologues thereof. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003220776-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7272545-B2 |
priorityDate |
1995-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |