| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_25165d41188a49e39f7fc20c8ee6a241 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-14 |
| filingDate |
2002-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2006-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cb345682c7c7aa508ff058cfe0c92b2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_550046c52582d7a81b2e4c6e9b2402c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_268260bacedfd7a608c5be2f43351b29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efe1a8a14d68acb1a819c692ed02045f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9edbc27470910b42ffb652a13e8ea46b |
| publicationDate |
2006-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7064209-B2 |
| titleOfInvention |
Process for producing optically active oxoheptenoic acid ester |
| abstract |
A novel process for producing an optically active (E)-7-[2-cyclopropyl-4-(4-fluorophenyl quinolin-3-yl]-5-hydroxy-3-oxohept-6-enoic acid ester of formula (III) which is important as an intermediate for synthesizing medicines, comprises reacting 1,3-bis(trimethylsilyloxy)-1-alkoxybuta-1,3-diene of formula (I) with (E)-3-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-prop-2-en-1-al of formula (II) in the presence of an optically active binaphthol-titanium complex obtained from 1,1′-bi-2-naphthol with titanium tetraisopropoxide, a metal salt and an amine, and then subjecting the reaction product to desilylation |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005070605-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013237563-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8912333-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7371865-B2 |
| priorityDate |
2001-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |