Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f7f665a5b37078501535a1089f71a78 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 |
filingDate |
2001-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2006-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56efb8776d3a6d41e0f5f61abf976e2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_251d91055fdb25ffe93b66b8792949d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9931cf40a3beab36483de7ce48bd098 |
publicationDate |
2006-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7053061-B2 |
titleOfInvention |
Amphotercin B structured emulsion |
abstract |
Parenteral compositions of oil-coated-Amphotericin B in structured-emulsion form, having LD50 of at least 400 mg/kg in mice and process for making the same have been described. The process essentially requires dispersing Amphotericin B in oily vehicle and dispersing emulsifier in the aqueous phase. The process of present invention is simple, cost effective and gives a stable product suitable for parenteral administration. Amphotericin B emulsion compositions prepared by the process of the present invention may be administered to human beings and animals for the treatment of fungal infections, with substantially equivalent or greater efficacy and low drug toxicity as compared to the conventional composition containing Amphotericin B and sodium desoxycholate. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008262084-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010273728-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011212167-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8673866-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9750812-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8592382-B2 |
priorityDate |
2000-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |