http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7041832-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_521dd8fecfba6eed22fef025ef85192b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10 |
filingDate | 2003-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2006-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cdf9ebdbba217b8081464177c881cbd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_858b01c0bc0e066768c7ecdcaa4ef497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4cf387fc7a1495f32c34b5de171bf06 |
publicationDate | 2006-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-7041832-B2 |
titleOfInvention | Processes for preparing losartan and losartan potassium |
abstract | Losartan is prepared by acid catalyzed cleavage of a triarylmethyl group from a triarylmethyl-substituted losartan derivative in a diluent comprising liquid ketone. The reaction mixture is basified and liquid ketone is evaporated from the mixture leaving a residue from which a triarylmethyl alcohol and losartan are each obtained in high yield and high purity. In addition, losartan potassium is prepared by a process that is more convenient that those previously known in the art in which losartan is contacted with potassium ions in substantially pure liquid alcohol and losartan potassium is precipitated from the alcohol. |
priorityDate | 2002-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 151.