| abstract |
A compound represented by the general formula: n nwherein R 20 is —CH 2 COOH and the like; R 21 is —COCONH 2 and the like; R 22 is C4–C6 alkyl; and the like; R 23 is —CH 2 —R 18 wherein R 18 is aryl and the like; R 24 is hydrogen or C1–C6 alkyl and the like; an optical active compound, a prodrug thereof, or a pharmaceutically acceptable salt, or a solvate having type X sPLA 2 inhibitory effect was found. |