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filingDate 2003-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2006-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_220d3728b6705f70dee18c1c8178a99f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7eb9e572648d9915515b9a2209547a19
publicationDate 2006-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-7026147-B2
titleOfInvention α-2,3-Sialyltransferase polypeptides
abstract This invention provides prokaryotic glycosyltransferases, including a bifunctional sialyltransferase that has both an α2,3- and an α2,8-activity. A β1,4-GalNAc transferase and a β1,3-galactosyltransferase are also provided by the invention, as are other glycosyltransferases and enzymes involved in synthesis of lipooligosaccharide (LOS). The glycosyltransferases can be obtained from, for example, Campylobacter species, including C. jejuni . In additional embodiments, the invention provides nucleic acids that encode the glycosyltransferases, as well as expression vectors and host cells for expressing the glycosyltransferases.
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