http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7005139-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4637fb4664424d470a4d02a738cec9f0 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
| filingDate | 2001-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfffcc49ff5a8ba8f1bd4fd11f9dd01e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0a3ec57652a98bef5f01d95526ab3d2 |
| publicationDate | 2006-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7005139-B2 |
| titleOfInvention | Compositions and methods for the targeted delivery of agents to treat liver cancer |
| abstract | The invention provides compositions containing an effective amount of a therapeutic agent encapsulated in a liposome coupled to a desialyated glycoprotein, e.g., desialyated glycoprotein-α1. This invention further provides methods for the targeted delivery of a therapeutic agent to a tissue expressing asialoglycoprotein receptors by delivery to the tissue an effective amount of a composition containing an effective amount of the agent encapsulated in a liposome coupled to a desialyated glycoprotein, e.g., desialyated glycoprotein-α1. Also provided by this invention is a method for inhibiting the proliferation of liver cancer by administering to a subject in need of such therapy an effective amount of a composition containing doxorubicin encapsulated in desialyated glycoprotein-α1 coupled to a liposome. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11541110-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008260725-A1 |
| priorityDate | 2001-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 239.