Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_23a4e0c875bf1ac2b8a3b76517de6c7d |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1272 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
filingDate |
2000-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2005-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d2b6616e6268b056d26cb874d22e163 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_582a10717a16f5ac77afc87398fb810c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfeef7f0ea68f9f3523ae2b81824285a |
publicationDate |
2005-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6979460-B1 |
titleOfInvention |
Vinyl ether lipids with cleavable hydrophlic headgroups |
abstract |
A novel amphiphilic lipid compound having a cleavable, vinyl ether linked hydrophilic headgroup is described. Also described are liposomes containing the vinyl ether lipid compound, which may be triggered to release their contents and/or permeablize or fuse with target lipid membranes. The cleavable vinyl ether linkage allows the hydrophilic headgroup to be dissociated from the hydrophobic tailgroup(s) of the lipid compound to facilitate phase transitions in the lipid bilayer. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2428235-A3 |
priorityDate |
1999-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |