| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bba710e7aaa56d8ab15a910fcd3dc5f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
| filingDate |
2000-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2005-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b175d26a10204a962344818ae9442db2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8de9ba22f97345b63ed52e8779a943d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1868d1554eca54feff6687a7740c4cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af2308d2b2bbe271590b34e534b56284 |
| publicationDate |
2005-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6958215-B1 |
| titleOfInvention |
Methods and compositions for inhibition of RNA splicing |
| abstract |
A method of inhibiting the self-splicing of a Group I intron is disclosed. The method uses an oligonucleotide having a sequence essentially identical to a guide sequence found in the 5′ flanking exon and terminates with a 3′ ribonucleoside. Usually the oligonucleotide has N3′→P5′ phosphoramidate or N3′→P5′ thiophiosphoramidate linkages rather than phosphodiester linkages. A method of inhibiting the growth of organisms having Group I intron, particularly certain pathogenic fungi including P. carinii, C. albicans , and A. nidulans using the oglionucleotide is also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9309568-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9315862-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010029008-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006088864-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004030111-A1 |
| priorityDate |
1999-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |