| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2bc9a27619362fe2b04ccb65b3fc2258 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B6-0006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-227
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-223 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B8-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/F21V8-00 |
| filingDate |
2001-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2005-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a62b3e347ee8d413a7a74faad95f5d07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_288cfa94a05fc043daa7dd0732aeff38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b42b5822818acf3b655427a0d9973f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d1357e5309b1e2671d546d5697d8ae3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f20b2c1fe48c8985118ceac3dc80be8 |
| publicationDate |
2005-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6953569-B2 |
| titleOfInvention |
Mixed gas microbubble compositions |
| abstract |
A microbubble preparation formed of a plurality of microbubbles comprising a first gas and a second gas surrounded by a membrane such as a surfactant, wherein the first gas and the second gas are present in a molar ratio of from about 1:100 to about 1000:1, and wherein the first gas has a vapor pressure of at least about (760−x) mm Hg at 37 C., where x is the vapor pressure of the second gas at 37 C., and wherein the vapor pressure of each of the first and second gases is greater than about 75 mm Hg at 37 C.; also disclosed are methods for preparing microbubble compositions, including compositions that rapidly shrink from a first average diameter to a second average diameter less than about 75% of the first average diameter and are stabilized at the second average diameter; kits for preparing microbubbles; and methods for using such microbubbles as ultrasound contrast agents. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008015012-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8257338-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008269668-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005281747-A1 |
| priorityDate |
1993-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |