| abstract |
Disclosed are novel compounds of the formula n n nwherein M 1 is CH or N and M 2 is C(R 3 ) or N; R 1 is optionally substituted indolyl or an aza derivative thereof; R 2 is optionally substituted aryl or heteroaryl; and the remaining variables are as defined in the specification.n n Also disclosed are pharmaceutical compositions comprising the compounds of formula I. n Also disclosed are methods of treating various diseases or conditions, such as, for example, allergy, allergy-induced airway responses, and congestion (e.g., nasal congestion) using the compounds of Formula I. n Also disclosed are methods of treating various diseases or conditions, such as, for example, allergy, allergy-induced airway responses, and congestion (e.g., nasal congestion) using the compounds of formula I in combination with a H 1 receptor antagonist. |