http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6946270-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b9036c33bbe3f4ea428655b76200f7c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-62 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62 |
| filingDate | 2000-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2005-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eafc7c5c72a5d71682eff9ed32160c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc5ceabb4ecdd50303bada2fb441919a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef0099b44669fb2ab69aa7d21a8205c7 |
| publicationDate | 2005-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6946270-B1 |
| titleOfInvention | Process for producing HMG-CoA reductase inhibitors |
| abstract | The present invention relates to a process for producing a compound (II-a) or a compound (II-b), each of which is a hydroxylated product of a compound represented by the formula (I-a) (hereinafter referred to as compound (I-a)): n n nwhereinn R 1 represents a hydrogen atom, a substituted or unsubstituted alkyl, or an alkali metal, and R 2 represents a substituted or unsubstituted alkyl, or a substituted or unsubstituted aryl; or a ring-closed lactone form thereof (hereinafter referred to as compound (I-b)).n nwherein the process comprises:n treating the compound (I-a) or compound (I-b) in an aqueous medium comprising with a microorganism acting to hydroxylate compound (I-a) or compound (I-b), having no ability to sporulate and showing no hyphal growth, a culture of the microorganism, or a treated product of the culture, as an enzyme source; and collecting a hydroxylated product of compound (I-a) or compound (I-b) from the aqueous medium. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010217032-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008261273-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7470528-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8058037-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7897370-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009148916-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010062486-A1 |
| priorityDate | 1999-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 119.