| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16634
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55555
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-765
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-2624
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-50 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-765
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-50 |
| filingDate |
2001-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2005-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_925ab2c1971e0a8500a06b299216fb4d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b58febdf5965a73901362fd1f66b392
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6401cec7c9f331dd85bd0f21b3ade9b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1aee6da2801b1440476a28bf4a9491ab |
| publicationDate |
2005-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6933286-B2 |
| titleOfInvention |
Therapeutic delivery compositions and methods of use thereof |
| abstract |
The present invention relates to compositions and methods for treating infectious diseases and genetic disorders through gene therapy and intracellular delivery of antisense oligonucleotides or other nucleic acid sequences. In particular, compositions and methods using biologically active nononic reverse block copolymers are described. The reverse copolymers have an inner core of polyoxyethylene (POE) that is flanked on either end by polyoxpropylene (POP). The reverse block copolymers have the following formula: n n nwherein “b” represents a number such that the molecular weight of the hydrophobe (C 3 H 6 O) b is between approximately 750 and 20,000 Daltons and “a” represents a number such that the percentage of hydrophile (C 2 H 4 O) a is between approximately 1% and 90% of the weight of the block copolymer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009076481-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014143763-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8983570-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013126590-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10624952-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011091427-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11224635-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011041478-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008287387-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004162256-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8435557-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7381422-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009181919-A1 |
| priorityDate |
1991-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |