Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2901e694724c2a759f619944cb7d2a4 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 |
filingDate |
2003-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2005-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bc3a10e11db20392bd82e702e243aeb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f909ad95eb7c38bb9f09762e7054d7b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9266cc540849fa1515fa2b1ac1ae45e5 |
publicationDate |
2005-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6930124-B2 |
titleOfInvention |
Compounds derived from oxindoles and their therapeutic application in cancer treatment |
abstract |
The invention relates to compounds of formula (I) n n nin which R 5 is chosen from the group consisting of: n n nin which R 2 is a C 1 -C 3 alkyl groupn nin which X may be Cl, Br, or Fn nin which n is between 1 and 3, in the E or Z form, or a mixture of the two isomeric forms, possessing antimitotic, antiproliferative and antivascular properties through inhibition of the polymerization of tubulin into microtubules |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9718990-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9580622-B2 |
priorityDate |
2001-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |