http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6919437-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_785ac2b35073f5a6d251678e6fb31b6f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate | 1999-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2005-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60031834243c01279d852d533cb28e53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0792f0d22dfe7322a82bc3251e8e626d |
| publicationDate | 2005-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6919437-B1 |
| titleOfInvention | Synthetic methods and intermediates for triester oligonucleotides |
| abstract | Methods for the preparation of oligonucleotides having bioreversible phosphate blocking groups are disclosed. In one aspect, the present invention provides compounds comprising a sequence of nucleotide units that includes a first segment having at least one internucleoside linkage of formula:n n3′-O—P(X)(O − )—O-5′n nand a second segment having at least one internucleoside linkage of formula:n n3′-O—P(X)(Y 1 —(CH 2 ) q —Y 2 —Y 3 —Z)—O-5′n nwherein each of X, Y 1 , and Y 2 is, independently, O or S; q is 2 to about 4; Y 3 is C(═O) or S; and Z is aryl having 6 to about 14 carbon atoms or alkyl having from one to about six carbon atoms. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10669301-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111039977-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111039977-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10087208-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010022621-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11597744-B2 |
| priorityDate | 1998-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 263.