http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6919337-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-04 |
| filingDate | 2003-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2005-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bac779fa654c95bd3dae8a5bc791b4c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19f995b6784eefd3df27fbdde84709ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06edd76f224260a697febd4099587a66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1b5333fbf8685f8552be3359e9a9315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d307adc59d16aa5856a732733b3558ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_577ba354655c9c35bba31418155fd6c8 |
| publicationDate | 2005-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6919337-B2 |
| titleOfInvention | 8-Quinolinxanthine and 8-isoquinolinxanthine derivatives as PDE 5 inhibitors |
| abstract | A compound of formula (I) n n nR 1 is hydrogen or alkyl optionally substituted by hydroxy, alkoxy, or alkylthio, R 2 is hydrogen, alkyl, hydroxyalkyl, alkylcarbonyloxyalkyl, alkoxyalkyl, alkylthioalkyl, alkenyl, cycloalkylalkyl, heterocyclylalkyl, aralkyl in which the aryl ring thereof is optionally fused to a 5-membered heterocyclic group or is optionally substituted by one or more substituents selected from alkoxy, amino, alkylamino, dialkylamino, acylamino, halogen, hydroxy, aminosulfonyl, alkylaminosulfonyl, dialkylaminosulfonyl, alkylsulfonylamino or dialkylaminosulfonylamino, R 3 is hydrogen or alkyl optionally substituted by hydroxy, alkoxy, or alkylthio, R 4 is hydrogen or alkyl, R 5 is a quinolinyl, isoquinolinyl or oxodihydroisoquinolinyl group optionally fused to a 5-membered heterocyclic group and optionally substituted by one or more substituents selected from halogen, cyano, hydroxy, alkyl, hydroxyalkyl, alkoxyalkyl, alkylthioalkyl, alkoxy, alkylthio, alkenyl, alkoxycarbonyl, alkynyl, carboxyl, acyl, a group of formula —N(R 6 )R 7 , aryl optionally substituted by one or more substituents selected from halogen or alkoxy, or heteroaryl having 5 or 6 ring atoms attached through a ring carbon atom to the indicated carbon atom, and R 6 and R 7 are each independently hydrogen or alkyl optionally substituted by hydroxy or alkoxy or one of R 6 and R 7 is hydrogen and the other is acyl, or R 6 and R 7 together with the nitrogen atom to which they are attached denote a 5- or 6-membered heterocyclyl group. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006173181-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015158895-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8709477-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9200016-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7902360-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006106039-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007282105-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005187226-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7247639-B2 |
| priorityDate | 2000-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1284.