abstract |
A compound of the formula (I) n n nin which R 1 is —OR 11 , —SR 11 , —SOR 11 , —SO 2 R 11 , —NHR 11 , or —NR 12 R 13 , and R 11 , R 12 , and R 13 are as defined broadly in the text. R 2 is H, C 1 -C 6 alkyl, carbamoyl, or an ester group. R 3 is thienyl, pyridyl optionally substituted by halogen or C 1 -C 6 alkoxy; naphthyl optionally substituted by C 1 -C 6 alkoxy; dioxane fused phenyl; dioxacyclopentane fused phenyl; or optionally substituted phenyl. Y is CH or N. A process for preparing such compounds, pharmaceutical compositions containing such compounds, and a method of treating asthma using them are also disclosed and claimed. |