http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6900222-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 |
filingDate | 2000-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2005-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d7912f879dd78b0fa891d444ceb07e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3cb746fb12c2992c00fe859bdbdfcc1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd0e694cad6f7ffef567876b91981c5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20fd9e73623bad885e2dd0b458737dff |
publicationDate | 2005-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-6900222-B1 |
titleOfInvention | Pyrrolidinyl, piperdinyl or homopiperidinyl substituted (benzodioxan, benzofuran or benzopyran) derivatives |
abstract | The present invention concerns compounds of formula (I) n n na stereochemically isomeric form thereof, an N-oxide form thereof or a pharmaceutically acceptable acid addition salt thereon wherein —Z 1 —Z 2 — is a bivalent radical; R 1 , R 2 and R 3 are each independently selected from hydrogen, C 1-6 alkyl, hydroxy, halo and the like; or when R 1 and R 2 are on adjacent carbon atoms, R 1 and R 2 taken together may form a bivalent radical of formula; Alk is optionally substituted C 1-6 alkanediyl; the bivalent radical n n nis a substituted piperidinyl, an optionally substituted pyrrolidinyl, homopiperidinyl, piperazinyl or tropyl; R 5 is a radical of formula n n nwherein n is 1 or 2; p 1 is 0, and p 2 is 1 or 2; or p 1 is 1 or 2, and p 2 is 0; X is oxygen, sulfur or ═NR 9 ; Y is oxygen or sulfur; R 7 is hydrogen, C 1-6 alkyl, C 3-6 cycloalkyl, phenyl or phenylmethyl; R 8 is C 1-6 alkyl, C 3-6 cycloalkyl phenyl or phenylmethyl; R 9 is cyano, C 1-6 alkyl, C 3-6 cyclo-alkyl, C 1-6 alkyloxycarbonyl or aminocarbonyl; R 10 is hydrogen or C 1-6 alkyl; and Q is a bivalent radical. Processes for preparing said products, formulations comprising said products and their use as a medicine are disclosed, in particular for treating conditions which are related to impaired fundic relaxation. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005096378-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004167171-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7208495-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7273862-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007149558-A1 |
priorityDate | 1999-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 586.