| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_29800004a1adc1fb9b840e645d147be5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57446
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3046 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 |
| filingDate |
2000-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2005-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6049e4f292c17c41de417a63ea0199ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fa48fe7650a0d2c30db26d6c772e316
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_242a13ecb9cfd1958c9524ba302b787f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42fca4f53bf258771622c836f3871dcb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ac661ec57b7b439dba817d9f56b0eca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91ecb5a4b0a544bc92c72f7bef2c0d1e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba55af32f872436127eb328e7a6b0a4c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6a5a176e94fd01aafb507874697dd1f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c0c2b49ef8c3f74d8d53024dd559a4c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fec4d350316bc0ed5a82e23452d43eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2aaa681afa7a712b1eaa8698bbc608c4 |
| publicationDate |
2005-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6891023-B1 |
| titleOfInvention |
Antibodies and Fv fragment recognizing antigen IOR C2 |
| abstract |
Novel recombinant antibodies from murine antibody IOR C5 produced by the hybridoma deposited with the ECCC 97061101. The recombinant antibodies were obtained using recombinant DNA technology and are characterized in that they recognize antigen ior C2. The recombinant antibodies are specifically chimeric antibody, humanized antibody, and single chain Fv fragment. The chimeric antibody contains the variable domains of the murine immunoglobuline and the constant regions of the human immunoglobuline. The humanized antibody contains the constant regions of human immunoglobuline and has been specifically modified in the murine frameworks regions (FRs) and within the latter, in those areas that may result in an antigenic site for cells T. The Fv fragment contains the variable domains of murine immunoglobuline. The invention also relates to the utilization of recombinant antibodies derived from murine antibody ior C5 in the diagnosis and therapy of colorectal tumors, the metastasis thereof and recurrences. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012114679-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10444124-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016266016-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10267714-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8716247-B2 |
| priorityDate |
1999-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |