| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_caec7099b724bb45d2518787825aab94 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate |
2001-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2005-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec91a287548518039576b32142d9ee5a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de902c73f0d011c7c79c76ca971cb094
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2d2bade23f8e12482b6ec2875533dde
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea0939d1e426e920f947830b71aa8f0d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c9543419c70f66ef98004f30bd2433d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0e6a0c8342c247d0562f2b1160d93cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7b97d8fa4132b6b40dd13b28169e150
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a776d0a20d7bb205bf4cb5d18a45b53f |
| publicationDate |
2005-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6844436-B2 |
| titleOfInvention |
Preparing pyrazolopyrimidinone derivatives for the treatment of impotence |
| abstract |
A method for preparing pyrazolopyrimidinone derivatives and their pharmaceutically acceptable salts having efficacy on the treatment of impotence, one of male sexual dysfunctions. The method comprises the steps of: a) chlorosulfonating a pyrazolamide compound to obtain a chlorosulfonated compound; b) reacting the chlorosulfonated compound of step (a) with a primary amine to obtain a sulfonamide compound and c) performing an intramolecular cyclization of the sulfonamide compound of step (b) to produce the compound of formula below 1, wherein the steps b) and c) are performed in situ in alcohol by adding a base to the reaction mixture without workup after the step b) is completed. |
| priorityDate |
2000-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |