| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3c057a64761cd914160cad58a9e19b2b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6561
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D279-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D279-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 |
| filingDate |
2000-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2005-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9588d9ec276f7a22fd9ac76e35501178
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_076d77da9713d3c1c127855411a5beea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50e20829d1ce5bfe7268568a8270b1da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e84ae7b52d4917dd67459f6b961ee75f |
| publicationDate |
2005-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6841559-B1 |
| titleOfInvention |
Pyridinones to treat and prevent bacterial infections |
| abstract |
Novel pyridinones and their derivatives which are effective in treating or preventing Gram-negative bacterial infections are provided. The pyridinones are stable and easily derivatized; the methods by which these derivatizations occur is described. Two regioselective and functional group tolerant methods for the synthesis of the novel pyridinones are also provided. One such synthetic method involves reacting an imine and a Meldrum's acid derivative in solution. The other synthetic method is a solid phase synthesis of the pyridinones in which an imine is prepared bound to a solid support and a Meldrum's acid derivative is reacted with the imine. Novel imine intermediates useful in the solid phase and solution methods of synthesizing the pyridionones are also described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007082887-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7659364-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003120032-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7915417-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008311644-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7411066-B2 |
| priorityDate |
1999-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |