| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e94e708dadc7e06262765b676d455e8b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9adc9372db1af2453fade995568b686d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B06B2201-77 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B05B5-035
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B05B17-0615
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B05B5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/F23D11-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B05B1-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01J49-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62 |
| filingDate |
2002-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5a1b048e8fb6a5867bacecd6dfa64d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1320ee0a4646059c6072b2e73c9ad34 |
| publicationDate |
2004-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6827287-B2 |
| titleOfInvention |
High throughput method and apparatus for introducing biological samples into analytical instruments |
| abstract |
Provided is a system for delivering a liquid sample to an inlet of an analytical instrument. Included is an acoustic ejector driven by a drive system that generates drive signals provided to the ejector. The drive signals are generated with a pulse width sufficient to eject at least a portion of the liquid sample. A reservoir provided for holding the liquid sample is in operational arrangement with the acoustic ejector. A liquid sample voltage source is located within the reservoir, and the liquid sample voltage source is designed to provide a charge to the liquid sample. An analytical instrument voltage source is in operational arrangement with the analytical instrument and is designed to provide a voltage bias between the reservoir and the analytical instrument.In another aspect of the invention, provided is a method for delivering a liquid sample to an inlet of an analytical instrument. The method includes generating an acoustic drive signal, with a pulse width sufficient to eject at least a portion of the liquid sample below a short pulse limit. The drive signal is delivered to an acoustic ejector whereby the acoustic ejector generates an acoustic wave. The acoustic wave is directed into a reservoir holding the liquid sample, wherein the acoustic wave is focused substantially at a surface of the liquid sample. This design results in the emitting of at least a portion of the liquid sample. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007256684-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7557342-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007012000-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009272897-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007012000-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008107935-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7714274-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10128097-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9664647-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7989763-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007080246-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10388504-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9916970-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7958887-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10991562-B2 |
| priorityDate |
2002-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |