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publicationDate 2004-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6818627-B1
titleOfInvention Functional fragments of HIV-1 Vpr protein and methods of using the same
abstract Conjugated compositions comprising a fragment of HIV-1 Vpr or a non-HIV-1 Vpr protein conjugated to a therapeutic compound and methods of using the same to deliver therapeutic compounds to a cell's nucleus or for the preparation of drug delivery particles are disclosed. Functional fragments of HIV-1 Vpr and functional non-HIV-1 Vpr proteins, and pharmaceutical compositions comprising the same are disclosed. Methods of inhibiting cell proliferation and methods of treating an individual who has a hyperproliferative disease are disclosed. Methods of identifying compounds that inhibit Vpr protein binding to the p6 domain of p55 or to p6 protein and kits for performing such methods are disclosed.
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP25406
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4TRK3
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC0R4Y0
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP00346
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9V0D5
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9MZR1
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC0RFH2
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP00326
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9MZR8
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP00327
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA1AGC9
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID13645
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP25405
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ5HG86
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP28474
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID851620
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ3YS64
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP25720
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4TLL5
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ3YX11
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB2GKC8
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ865X6
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP25721
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID11886
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ865X5
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC1B155
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID10376
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP13603
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID7058172
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID64083
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP61889
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ865W7
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ28819
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA9A450
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP09459
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ865X2
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB2HZ52
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC1AMN4
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID505103
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4UHP8
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ2W064
http://rdf.ncbi.nlm.nih.gov/pubchem/taxonomy/TAXID11676
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB2HRH5
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP25988
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4UHQ3
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ867X2
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP26029
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ7VFV4
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB2IG85
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ867X3
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6991974
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP61897

Total number of triples: 1964.